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Libera Bio develops a new family of cancer treatments based on its patented actively targeted delivery technology to intracellular targets (MPN – Multifunctional Polymeric Nanocapsules) and on novel monoclonal antibodies (e.g. anti KRAS), with the goal to have them commercialized by large biopharma companies after regulatory approval for clinical trials or early proof-of-concept in humans.

Libera Bio lead candidate aims at providing a new treatment for those highly prevalent and aggressive cancers which are driven by KRAS mutations, such as pancreatic cancer, lung cancer and colorectal cancer.

Company:
Maculus Therapeutix is a preclinical-stage biopharmaceutical company focused on finding practical solutions to treat chronic diseases of the retina and optic nerve such as wetAMD (Age related Macular Degeneration) in the Ophthalmology space with a novel tunable biodegradable proprietary product – MacuBloc™ capable of delivering any FDA approved drugs for Wet AMD to the site of the disease. With its unique suitability for targeted and extended delivery of drugs to back of the human eyes, MacuBloc™ offers significant benefits to Wet AMD patients over existing products: a single intravitreal injection that lasts an year instead of the current 10-12 monthly injections plus significant potential reduction in inflammation, infection, doctor visits and total cost of care compared to current practice.

Market:
The global market size of Age-Related Macular Degeneration (AMD) is currently $7.7B, growing at 7.6% CAGR and is expected to reach a value of $11B by 2025. Current standard of care involves 10-12 monthly injections with a 30 gauge syringe needle going through the eye sclera, often resulting post-injection pain and possible infection due to repeated injections in a small area as well as ruptured blood vessels in the sclera. By reducing the number of injections from 10+ to just ONE, MacuBloc™ formulation is likely to be a treatment of choice.

MediBase Group is an ITALIAN industrial company that has been operating since 1995 in the field of phytotherapy and medical dietetics; was one of the first companies to deal with Nutraceuticals through the preparation of products addressed exclusively to the health care professionals and distributed through the pharmacies, nursing homes and hospitals.
Titration and standardization are the most important quality criteria in the preparation of MediBase products.
The formulation of our preparations, the choice of active ingredients and their titration are based on accurate studies and analyzes of clinical works, published in the most prestigious international scientific journals, by our R&D.

Digital physician platform for over 2.5 million registered Chinese doctors. We also help US pharma, biotech and medical device companies strategize and promote products and services directly to Chinese physicians.

Mission Bio unlocks the ground truth of cancer through response, relapse, and remission with its Tapestri Platform, powered by single-cell multi-omics. As the first and only to analyze genotype and phenotype simultaneously in single cells, the Tapestri Platform can help unravel the inherent complexity of cancer. The technology discerns key biomarkers to stratify patients more precisely, signal treatment resistance as it begins, and predict relapse for better patient outcomes. Application areas include blood cancers, solid tumors, and genome editing validation.

Researchers at Memorial Sloan Kettering Cancer Center (MSK), MD Anderson Cancer Center (MDACC), and the University of California at San Francisco (UCSF) have leveraged the Tapestri Platform to support their research for characterizing clonal dynamics in a variety of cancers, identifying minimal residual disease (MRD), and monitoring treatment response and therapy resistance. The company’s award-winning technology is also leveraged by LabCorp and Agios to enable more efficient clinical trials.

Nanovista is a biotechnology company based out of JLABS @ Toronto that is developing technologies to improve the outcomes of cancer surgeries. Nanovista’s lead program, CF800, is a novel imaging agent that enables the real-time visualization of solid tumors during cancer surgery.

Nenupharma was born out of a shared passion to contribute to the development of innovative pharmaceuticals in different disease areas.

Nenupharma uses the best of skills that have been developed through an extensive career in pharmaceutical industry, regulatory affairs, market access, medical practice and life science.

Nenupharma has been working with high level experts on different levels and enjoys reliable, professional and ethical reputation among its network as well as its customers.

For more information, visit our website at:
www.nenupharma.com

Neuro-Zone, since 13 years, supports drug discovery, drug repurposing and research projects in the fields of inflammation and age-related pathologies.
In particular, we have developed pathology-specific platforms to generate rapid and informative data on efficacy, toxicity, metabolism and mechanism of action, supported by proprietary technologies such as MicroTISSUE (dissecting microenvironment-cell interaction in complex inflammatory scenarios) or MITOS (a comprehensive analytical platform for quantitative analysis of mitochondrial function ).
Our approach enables effective selection and ranking of the most promising candidates per indication.
Moreover, we profile candidates at different level of complexity starting from:
a) pharmacology profiling (GPCR; Ion Channel receptors)
b) identification of biochemical pathways responsible for therapeutic efficacy (transcriptomics)
c) disease modified barrier permeability (BBB and endothelial)

We are a corporate finance firm committed to advancing the field of Healthcare through advisory,and investments.

We advise and buy-side and sell side corporates and Family offices on investment in Healthcare & life Sciences across Switzerland, Europe and the US.

华诺临床立足于海外,为全球客户提供医药产品在北美进行 FDA 临床报批、临床试验运营、临床数据分析与管理等一系列服务。专业的团队,丰富的经验以及客户至上的合作理念会助您拓展在海外的临床开发业务。客户的满意与成功是我们追求的终极目标。