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Founded in 2017, it has been the mission of Nanjing IASO Biotherapeutics (IASO BIO) to become a leading biopharmaceutical company focused on the discovery, development and commercialization of cell therapies in the field of oncology.

IASO BIO stands out through innovation, a world class facility, and an internationally renowned clinical research team that has treated more than 400 patients. Curing many who continually failed through multiple-lines of therapy, by means of detailed and thorough pathological analysis and follow up.

IASO BIO is dedicated to curing cancer using engineered autologous/allogenic T cell therapies designed to enhance the immune system's ability to recognize and eradicate cancer cells. Safety is dramatically enhanced via a proprietary procedure, minimizing the severity of CRS. Currently, IASO BIO is developing over 10 high-potential pharmaceutical products, targeting hematological tumors, solid tumors and virus associated tumors at different clinic stages.

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ImmunoBiochem has pioneered a proprietary technology to address the challenges of cancer heterogeneity and tumor penetration by biologics in solid tumors with its tumor microenvironment-targeted potentiated antibodies. ImmunoBiochem's biologics are aimed at targets amplified in the secretomes of cancer cells that enable selective and efficacious delivery of payloads in tumor cells, immune cells and tumor-supporting stroma within the tumor microenvironment. ImmunoBiochem is able to deliver novel immunomodulatory payloads to a variety of cell types within the tumor in a highly selective fashion, pioneering a next-generation strategy for the delivery of innate immune system modulators.

Incuron is a private clinical-stage company that develops a novel class of synthetic small molecules, Curaxins, with a unique multi-targeted mechanism of antitumor activity. These chromatin damaging agents interfere with histone/DNA binding causing decondensation of chromatin in tumor cells, functional inactivation of histone chaperone FACT, and simultaneous effect on a set of universal previously undruggable targets, leading to inhibition of pro-cancer transcriptional factors, MYC, NF-kB, HIF1a, and HSF-1, and activation of the tumor suppressor p53, as well as induction of type I interferon response.
Key advantages of curaxins based on current preclinical and early clinical data include:
- novel mechanism of action that would bring the additional treatment option for advanced and relapsed tumors, as well as potential to overcome resistance to previous treatments;
- favorable pharmacology and manageable safety profiles;
- low potential for serious drug-drug interactions providing opportunities for combinatorial therapeutic regimens;
- broad activity in different tumor types that may open wider market opportunities;
- focused phase 2 clinical study program can establish faster clinical proof of concept and build toward accelerated regulatory approval.
Incuron owns a worldwide patent portfolio, including the composition of matter and therapeutic uses of the compounds.

iNNOGING Medical - Remote and offline ultrasound image analysis solution

Ultrasound is a real-time examination and very much operator dependent.
Majority of ultrasound scans are done by technicians and afterwards diagnosed off-line by the expert without the presence of the patient. A major drawback is that the radiologist who determines the diagnoses is not the person who performs the ultrasound scan; hence this workflow might lead to errors and worse to misdiagnoses.
iNNOGING is developing a technology that will provide the radiologists a remote and off-line tool to inspect areas of interest, based on recorded ultrasound scans. Allowing navigation like in real time as if the patient is there with the doctor, while all possible information (any plane) of an organ is visible, even information that was not presented in the original scan.

In addition to the above, we have recently launched an affordable SaaS based Ultrasound Simulator.

INOVOTION is a biotech company which offers you a unique in vivo technology dedicated to oncology and immuno-oncology efficacy studies and early toxicity evaluations.
Our Fast, Sensitive, Reliable and Affordable assay will save you time and money, to give you a clear competitive advantage.
This breaking-thought technology, based on chick embryo, provides early analysis of your anti-cancer treatments before the classical preclinical stages. By eliminating low-value molecules early, INOVOTION accelerates your drug discovery process, increases your R&D productivity and reduces its costs.
It’s rapid Go/No Go decision with multi-cancer screening capacities.
This next generation of in vivo efficacy and toxicity tests covers fours main aspects:
- EFFICACY assays for your treatments in oncology and immuno-oncology
- EARLY TOXICITY assays for your drug candidates
- TARGET VALIDATION in oncology
- MULTI-CANCER SCREENING to (re)positioning your treatment

InvivoSciences, Inc. (IVS) is a preclinical stage biotech company with a team of drug development experts, including Dr. Joseph Schlessinger, who developed various therapies including, a blockbuster drug - Sutent.
With an increasingly aging population with chronic diseases such as diabetes, heart failure is an urgent and critical challenge without an effective solution. There have been no successful phase III trials in worsening chronic heart failure or heart failure with preserved ejection fraction (HFpEF). Large clinical trials required for the heart failure trials have been the bottleneck. There is clear evidence showing that genetic factors drive heart failure development. Our mission is to cure heart failure one gene at a time.
We have leveraged our advanced artificial intelligence integrated breakthrough in precision medicine discovery platform using patient-derived human micro heart on a chip, NuHeart™, to identify and validate multiple drug pipelines rapidly as well as help us to determine biomarkers and stratify the patients for a clinical trial recruitments. Our precision heart failure pipelines are at least ten times more cost-effective to develop, especially during their clinical stages. Using our platform, we have developed two pipelines of small-molecule candidates for difficult to treat, genetically defined heart failure conditions. Our Pipelines of precision medicines have the potential to deliver better outcomes for patients fighting hard to treat heritable heart disease.
Collaborative patient-driven precision medicine-based drug development empowered with our novel platform will lead to meaningfully better outcomes for heart failure patients, which we refer to as InvivoSciences’ discovery engine to develop target therapies. Our lead program includes candidates in preclinical development for monogenetic heart failures. To date, IVS raised $8.5 Million non-dilutive funding from founders, board, commercial contracts, and grants. The funds have been used to create a portfolio of assets (breakthrough discovery platform, NuHeart™, three genetically defined disease models, current discovery programs, and a strong portfolio of patents including both US and international.
To join and support our drug discovery programs forward, InvivoSciences is seeking world-class life science investors and strategic partners for our Series A round for growth capital for $10 M in two trunches for commercial growth and accelerating our drug program.